Understanding PANS and PANDAS: A Guide for Concerned Parents

Understanding PANS and PANDAS: A Guide for Concerned Parents

When a child suddenly develops severe anxiety, obsessive-compulsive behaviors, or motor tics—seemingly overnight—it can be overwhelming and frightening for parents. In many cases, these symptoms may be more than a phase or a psychological issue. They could be signs of PANS or PANDAS, two immune-related conditions that affect children’s brain function. If you’re seeking help from professionals who understand these disorders, Level Up Wellness Group in Canada offers integrated care and resources tailored to families facing this challenge.

What Are PANS and PANDAS?

PANDAS: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections

PANDAS is a condition triggered by a streptococcal (strep) infection. In some children, the immune system mistakenly attacks part of the brain—specifically the basal ganglia—leading to sudden onset of neuropsychiatric symptoms such as:

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Obsessive-compulsive behaviors

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Tics (involuntary movements or vocalizations)

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Severe separation anxiety

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Mood swings and irritability

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Bedwetting or sleep disruptions

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Regression in handwriting, speech, or academics

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PANS: Pediatric Acute-onset Neuropsychiatric Syndrome

PANS is a broader diagnosis that includes similar symptoms but isn’t limited to strep infections. It can be triggered by other infections (like the flu or Lyme disease), environmental toxins, or stress. Key characteristics include:

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Abrupt onset of OCD or restrictive eating

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Anxiety, aggression, or depression

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Cognitive decline

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Sensory issues or motor abnormalities

How Infections Affect the Brain

In both PANS and PANDAS, the immune system reacts abnormally to a trigger, causing inflammation in the brain. This inflammation disrupts normal behavior and function, creating a sudden and dramatic shift in the child’s mental and emotional state. For many parents, it’s shocking—children who were once happy and healthy may become fearful, angry, or withdrawn within days.

Diagnosing PANS and PANDAS

Diagnosis can be tricky because there’s no single test for either condition. Clinicians must rule out other causes while evaluating symptom patterns. The diagnosis typically includes:

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Reviewing the child’s complete medical and behavioral history

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Testing for recent infections and immune responses

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Assessing cognitive, emotional, and physical symptoms

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Ruling out psychiatric or neurological disorders

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Because these conditions are still gaining recognition, many families go months or even years before receiving a correct diagnosis. That’s why working with experienced providers—like those at Level Up Wellness Group—can be so critical.

Why Early Intervention Is Crucial

Early treatment offers the best chance of full recovery. When left untreated, PANS and PANDAS can lead to chronic issues like social isolation, academic failure, and ongoing emotional distress. Prompt intervention with a multidisciplinary team can significantly improve outcomes and prevent long-term effects.

Treatment Approaches: Medical, Psychological, and Holistic

There is no universal treatment for PANS or PANDAS. A comprehensive plan typically includes:

1. Medical Management

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Antibiotics: To treat any underlying infection

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Anti-inflammatories or steroids: To reduce brain inflammation

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Immune therapy (e.g., IVIG): In more severe cases

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2. Psychological Support

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Cognitive Behavioral Therapy (CBT): To address OCD and anxiety

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Exposure and Response Prevention (ERP): For behavior modification

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Family Therapy: To support parents and siblings

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3. Holistic and Integrative Therapies

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Nutritional counseling to reduce inflammation and boost immunity

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Occupational or speech therapy for developmental regressions

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Mind-body techniques such as yoga or mindfulness for emotional balance

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Providers that use an integrative approach—combining physical, mental, and emotional therapies—are often the most effective at treating the full scope of these disorders.

The Emotional Toll on Families

Living with a child affected by PANS or PANDAS is stressful and often isolating. Parents may experience:

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Burnout from caregiving

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Financial strain from missed work or therapy costs

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Guilt or confusion about their child’s condition

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Frustration over misdiagnosis or lack of understanding from doctors

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Connecting with a knowledgeable care team and support networks can offer guidance and much-needed relief during this challenging time.

Helpful Tips for Parents

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Document everything: Keep a detailed log of symptoms, triggers, and treatments.

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Find experienced providers: Choose a team that understands PANS and PANDAS, not just general mental health.

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Advocate for your child: You may need to push for tests or referrals—don’t be afraid to ask questions.

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Be patient with recovery: Healing isn’t always linear. Flare-ups can happen, but progress is possible.

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Take care of yourself too: Your mental and physical health are essential to supporting your child.

When to Seek Help

If your child is showing abrupt changes in mood, personality, or behavior after an illness—especially strep—don’t wait. Reach out to a trusted provider who is familiar with PANS and PANDAS. Early treatment is essential for recovery and reducing long-term impacts.

Organizations like Level Up Wellness Group offer services designed for families facing these specific challenges, with access to multidisciplinary therapies and compassionate care.

Final Thoughts

PANS and PANDAS are often misunderstood and underdiagnosed, but they are real conditions that deserve serious attention. With proper care, many children recover fully and go on to lead happy, healthy lives. If you’re a parent struggling to find answers, you’re not alone—and there are effective resources and professionals ready to help.

Don’t hesitate to seek support and guidance. The earlier you intervene, the better the chances for healing and long-term success.

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